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[Phosphoramidites]Long trebler phosphoramidite

Long trebler phosphoramidite

訂購貨號產(chǎn)品名稱及規(guī)格價格(￥)

24260Long trebler phosphoramidite, 250 mg3250.00

34260Long trebler phosphoramidite, 500 mg4550.00

44260Long trebler phosphoramidite, 1 g7800.00

Long trebler phosphoramidite is a branching reagent for oligonucleotide synthesis allowing to synthesize branched DNA structures using standard DNA synthesizer.

After the condensation of the trebler, three DNA branches begin to grow simultaneously with each step of the synthesis. Deblock of this construct gives rise to DNA containing branching point. One arm (stem) is attached to branch point with its 5'-end, and other arms (branches) are attached via 3'-end. Reverse amidites can be used to prepare constructs with different branch orientations. Repetitive condensations of trebler results in formation of DNA dendrimers.

Trebler amidite can be used to attach several modifier amidites to 5'-end of oligonucleotide - for example, three biotin residues can be attached at once.

This amidite does not require any special handling. Recommended coupling time is 5 minutes. No changes to deblock conditions are required.

General properties

Appearance: viscous yellowish oil

Molecular weight: 1475.78

Molecular formula: C89H107N2O15P

Solubility: soluble in acetonitrile, dichloromethane

Quality control: NMR 1H (95%), 13C, 31P, HPLC

Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

MSDS: Download

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